发明名称 |
BIARYL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND AGENT |
摘要 |
A compound represented by the formula (I) [wherein rings A and B each represents an optionally substituted five- or six-membered aromatic ring; R<1> and R<2> each represents hydrogen, an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group; X<1>, X<2>, X<3>, and X<4> each represents a bond or an optionally substituted divalent hydrocarbon group; Y represents -NR<3>-CO-, -CO-NR<3>-, -NR<3>-SO2-, -SO2-NR<3>-, -NR<3>-CH2- (R<3> represents hydrogen, an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group), etc.; Z represents -CO-NH-, -CS-NH-, -CO-, or -SO2-; and Ar represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group] or a salt of the compound. The compound or salt functions to increase the amount of a low-density lipoprotein (LDL) receptor and is useful as a blood lipid depressant, etc. Also provided is a medicine or the like containing the compound or salt.
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申请公布号 |
WO02055484(A1) |
申请公布日期 |
2002.07.18 |
申请号 |
WO2002JP00073 |
申请日期 |
2002.01.10 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD.;KORI, MASAKUNI;ISHIKAWA, EIICHIRO;NAKATA, MIKIYO;KOBAYASHI, MAKOTO |
发明人 |
KORI, MASAKUNI;ISHIKAWA, EIICHIRO;NAKATA, MIKIYO;KOBAYASHI, MAKOTO |
分类号 |
A61P3/06;A61P3/10;A61P9/10;C07C311/18;C07D213/40;C07D213/75;C07D213/81;C07D213/82;C07D307/14;C07D333/20;C07D401/12;C07D405/12;C07D409/12;C07D417/12;(IPC1-7):C07C233/78;C07C233/80;C07C271/08;C07C271/40;C07C275/28;C07C311/01;C07C311/15;C07C311/30;C07C335/16;C07D213/56;C07D307/52;A61K31/17;A61K31/341;A61K31/381;A61K31/440;A61K31/443;A61K31/506 |
主分类号 |
A61P3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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