| 发明名称 |
POLYPEPTIDE TAGGING FUSIONS AND METHODS |
| 摘要 |
This disclosure describes fusion polypeptides and complexes, compositions, and methods involving the fusion polypeptides. Generally, the fusion polypeptides include at least a portion of a protein of interest and at least a functional portion of a HUH polypeptide. Generally, the functional portion of a HUH polypeptide includes at least a portion of a Rep/relaxase domain that includes at least one catalytic polar amino acid residue and at least one metal-coordinating amino acid residues. |
| 申请公布号 |
US2016340395(A1) |
申请公布日期 |
2016.11.24 |
| 申请号 |
US201615159381 |
申请日期 |
2016.05.19 |
| 申请人 |
REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
Gordon Wendy Ryan;Lovendahl Klaus Norman |
| 分类号 |
C07K14/47;G01N33/53;C12N9/22 |
主分类号 |
C07K14/47 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A fusion polypeptide comprising:
at least a portion of a polypeptide of interest; and at least a functional portion of an HUH polypeptide Rep/relaxase domain, wherein the HUH polypeptide Rep/relaxase domain comprises:
at least one catalytic polar amino acid residue; andat least one metal-coordinating amino acid residue. |
| 地址 |
MINNEAPOLIS MN US |
