CALPAIN INHIBITORS FOR IBD AND COLORECTAL CANCER TREATMENT

摘要

The present disclosure provides a method of treating colitis and colorectal cancer with a m-calpain selective inhibitor. Also described in this disclosure are pharmaceutical compositions comprising a m-calpain selective inhibitor to inhibit m-calpain activity in tumor cells and other cells in the colon.

主权项

1. A method of treating colorectal cancer or inflammatory bowel disease, comprising administering to a subject in need thereof, a therapeutically effective amount of a pharmaceutical composition comprising a m-calpain selective inhibitor, or a pharmaceutically acceptable salt, solute, or hydrate thereof.