发明名称 |
PHARMACEUTICAL TETRACYCLINE COMPOSITION FOR DERMATOLOGICAL USE |
摘要 |
Provided herein is a topical composition and related methods for making and using the composition. In a first aspect, the topical composition comprises minocycline, a magnesium salt, and a sulfite compound in a non-aqueous solvent. In yet another aspect, the topical composition comprises a tetracycline-class drug, a source of magnesium, a monohydric aliphatic alcohol, and a polyol, wherein (i) the ratio between the monohydric aliphatic alcohol and the propylene glycol is in the range of 1:1 to 99:1 by weight and (ii) the tetracycline-class drug is dissolved in the topical composition. |
申请公布号 |
WO2016154232(A2) |
申请公布日期 |
2016.09.29 |
申请号 |
WO2016US23646 |
申请日期 |
2016.03.22 |
申请人 |
BIOPHARMX, INC. |
发明人 |
CHEN, Xin;HERMSMEIER, Maiko, C.;LAC, Diana;THOMAS, Douglas, W.;YAM, Noymi;YAMAMOTO, Akira |
分类号 |
A61K9/00;A61K31/65;A61K47/02;A61K47/10 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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