| 发明名称 |
IDENTIFICATION OF NOVEL BIOMARKERS OF FLARES OF SYSTEMIC LUPUS ERYTHEMATOSUS |
| 摘要 |
The present invention relates to methods for diagnosing or monitoring the flare status of subjects with Systemic Lupus Erythematosus (SLE). More particularly, the present invention relates to testing fluid samples from subjects for differentially expressed biomarkers, and kits for performing the tests. |
| 申请公布号 |
US2016223537(A1) |
申请公布日期 |
2016.08.04 |
| 申请号 |
US201415021225 |
申请日期 |
2014.09.11 |
| 申请人 |
SINGAPORE HEALTH SERVICES PTE LTD |
发明人 |
FONG KOK YONG;THUMBOO JULIAN;THIO SZU-TIEN;TONG HAK TIEN LOUISE-MARIE GRIGNION;ZHOU LEI |
| 分类号 |
G01N33/564;C12Q1/68 |
主分类号 |
G01N33/564 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of analysing a fluid test sample from a subject, comprising a step of determining the level of at least one biomarker in the test sample and comparing said level to that in a reference sample, wherein the at least one biomarker is selected from the group comprising Enolase 1 (ENO1), Deleted in Brain Tumour 1 (DMBT1), Lactate dehydrogenase A (LDHA) or Lactate dehydrogenase B (LDHB) and Heat Shock 70 kDa Protein 1 B (HSPA1 B) and Heat Shock 27 kDa Protein 1 (HSPB1). |
| 地址 |
Singapore SG |
