Ω-3 FATTY ACID SELF-EMULSIFYING COMPOSITION

摘要

A pharmaceutical self-emulsifying composition containing, relative to 100 mass% of the entire self-emulsifying composition: 70-90 mass% ethyl eicosapentaenoic acid as a first medicinal component; 0.5-6.0 mass% water; 1-29 mass% of a polyoxyethylene sorbitan fatty acid ester (optionally including polyoxyethylene castor oil) as an emulsifier; 1-25 parts by mass of lectin per 100 parts by mass of the ethyl eicosapentaenoic acid; and Pitavastatin, Rosuvastatin or a salt thereof as a second medicinal component. This pharmaceutical self-emulsifying composition exhibits superior self-emulsification properties, composition dispersion properties, emulsion stability, absorption properties, medicinal component storage stability and preparation storage stability.