主权项 |
1. A method of producing a compound of formula (I): or a salt thereof, wherein R1 is selected from the group consisting of H, unsubstituted or substituted C1-C10 alkyl, and unsubstituted or substituted C2-C10 alkenyl, and R2 is selected from the group consisting of H, unsubstituted or substituted C1-C10 alkyl, and CORa, in which Ra is H or unsubstituted or substituted C1-C10 alkyl, the method comprising:
reacting a compound having the formula IB with ozone and subsequently with an oxidant different from ozone to obtain the compound of formula (I) wherein R1 is H; or alternatively
reacting a compound having the formula (IB) with ozone and subsequently with a reductant to obtain a mixture comprising the compound of formula (I) wherein R1 is H and a compound of formula (IC): and
separating the compound of formula (I) wherein R1 is H from the compound of formula (IC). |