发明名称 |
HUMAN ANTIBODIES TO INFLUENZA HEMAGGLUTININ |
摘要 |
The present invention provides monoclonal antibodies, or antigen-binding fragments thereof, that bind to the influenza hemagglutinin (HA) protein, pharmaceutical compositions comprising the antibodies and methods of use. The antibodies of the invention are useful for inhibiting or neutralizing influenza virus activity, thus providing a means of treating or preventing influenza infection in humans. In some embodiments, the invention provides for use of one or more antibodies that bind to the influenza HA for preventing viral attachment and/or entry into host cells. The antibodies of the invention may be used prophylactically or therapeutically and may be used alone or in combination with one or more other anti-viral agents or vaccines. |
申请公布号 |
WO2016100807(A3) |
申请公布日期 |
2016.08.04 |
申请号 |
WO2015US66654 |
申请日期 |
2015.12.18 |
申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
PURCELL NGAMBO, LISA, A.;VIAU, JONATHAN;OLSON, WILLIAM |
分类号 |
C07K16/10;A61K31/215;A61K39/42 |
主分类号 |
C07K16/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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