PROCESS FOR PRODUCING SUGAR CHAIN ASPARAGINE DERIVATIVE

摘要

Production of sugar chain asparagine derivatives comprises: (a) obtaining a mixture of sugar chain asparagine derivatives by introducing a fat-soluble protecting group into a mixture of at least one sugar chain asparagine derivative; (b) separating sugar chain asparagine derivatives or their hydrolyzates by chromatography, and (c) removing the protecting group. Independent claims are also included for the following: (1) new sugar chain asparagine derivatives of formula (I)-(III), and (2) sugar chains of formula (IV). [Image] R 1>, R 2>H or a group of formula (i)-(iv); one of R x>, R y>H and the other is group of formula (v), or (i)-(iv), and R 3>-R 6>H or (i)-(iv), provided that: (1) R 1> and R 2> are not both (ii); (2) R 3> and R 4> are not both (v) or (i), and (3) R 5> and R 6> are not both (i)-(iv). [Image].