| 发明名称 |
METHOD OF TREATING OF DEMYELINATING DISEASES OR CONDITIONS |
| 摘要 |
<p>N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.</p> |
| 申请公布号 |
SG134170(A1) |
申请公布日期 |
2007.08.29 |
| 申请号 |
SG20050058029 |
申请日期 |
2002.02.14 |
| 申请人 |
AVENTIS PHARMACEUTICALS INC. |
发明人 |
SMITH,CRAIG, P.;RATHBONE, MICHEL, P.;PETTY, MARGARET;RAMPE, DAVID |
| 分类号 |
C07D401/12;A61K;A61K31/4439;A61P3/00;A61P9/00;A61P13/00;A61P13/10;A61P17/02;A61P19/02;A61P25/00;A61P25/02;A61P25/28;A61P27/02;A61P29/00;A61P35/00;(IPC1-7):A61K31/443 |
主分类号 |
C07D401/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
