| 主权项 |
1. A compound selected from
(S)-8-((2-amino-4-methylpentyl)oxy)-9-bromobenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-methylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-isobutyl-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-((2-amino-5,5,5-trifluoropentyl)oxy)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-((2-amino-5,5,5-trifluoropentyl)oxy)-9-bromo-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-((2-amino-5,5,5-trifluoropentyl)oxy)-9-chloro-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 4-amino-8-((2-amino-5,5,5-trifluoropentyl)oxy)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-(difluoromethyl)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-bromo-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-((2-amino-5,5,5-trifluoropentyl)oxy)-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-((2-amino-5,5,5-trifluoropentyl)oxy)-9-chloro-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-cyclopropyl-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-((2-amino-5,5,5-trifluoropentyl)oxy)-6-methyl-5-oxo-5,6-dihydrobenzo[c][2,7]naphthyridine-9-carbonitrile; 8-((2-amino-5,5,5-trifluoropentyl)oxy)-9-bromo-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-isopropyl-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-bromo-6-(2-methoxyethyl)-4-methylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-chloro-6-(2-hydroxyethyl)-4-methylbenzo[c][2,7]naphthyridin-5(6H)-one; (R)-8-((2-amino-4-methylpentyl)oxy)-9-bromo-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-bromo-7-fluoro-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-(2-amino-4,4,4-trifluorobutoxy)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-(2-amino-4,4,4-trifluorobutoxy)-9-bromo-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-(2-amino-4,4,4-trifluorobutoxy)-9-bromo-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-(2-amino-4,4,4-trifluorobutoxy)-9-chloro-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-chlorobenzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-amino-4-methylpentyl)oxy)-9-bromo-6-(2-hydroxyethyl)-4-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-methoxy-4, 6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; (S)-1-(8-((2-amino-4-methylpentyl)oxy)-9-fluoro-6-methyl-5-oxo-5,6-dihydrobenzo[c][2,7]naphthyridin-4-yl)-3-methylurea; 8-(2-hydroxy-3-(isopropylamino)propoxy)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-(2-hydroxy-3-(isopropylamino)propoxy)-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 9-bromo-8-(2-hydroxy-3-(isopropylamino)propoxy)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 9-bromo-8-(2-hydroxy-3-(isopropylamino)propoxy)-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-((2,4-dimethylpentyl)oxy)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 6-methyl-8-((4-methylpentyl)oxy)benzo[c][2,7]naphthyridin-5(6H)-one; (S)-8-((2-hydroxy-4-methylpentyl)oxy)-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-(2-hydroxy-3-isopropoxypropoxy)-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 9-bromo-8-((2,4-dimethylpentyl)oxy)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; 8-((2,4-dimethylpentyl)oxy)-4,6-dimethylbenzo[c][2,7]naphthyridin-5(6H)-one; 4,6-dimethyl-8-((4-methylpentyl)oxy)benzo[c][2,7]naphthyridin-5(6H)-one; and 8-((2,4-dimethylpentyl)oxy)-6-methylbenzo[c][2,7]naphthyridin-5(6H)-one; or a pharmaceutically acceptable salt thereof. |
