发明名称 |
PERFLUOROALKYL-CONTAINING COMPLEXES WITH POLAR RESIDUES, METHOD FOR THEIR PREPARING, PHARMACEUTICAL AGENT |
摘要 |
FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention describes perfluoroalkyl-containing complexes with polar residues of the general formula (I): ^ wherein R means a polar residue; G means a trifunctional residue, a perfluorinated carbon chain; K means a metal complex; Z means a linker group. Proposed complexes can be used for intravenous lymphography, tumor diagnosis and for visualization of infarctions and necrosis. Also, invention describes a method for synthesis of these complexes. ^ EFFECT: valuable medicinal properties of complexes. ^ 16 cl, 1 tbl, 26 ex |
申请公布号 |
RU2289579(C2) |
申请公布日期 |
2006.12.20 |
申请号 |
RU20030105813 |
申请日期 |
2001.07.23 |
申请人 |
SHERING AKTSIENGEZEL'SHAFT |
发明人 |
PLATTSEK IOGANNES;MARESKI PETER;NIDBALLA UL'RIKH;RADJUKHEL' BERND;VAJNMANN KHANNS-JOAKHIM;MISSEL'VITTS BERND |
分类号 |
C07D257/12;C07D295/22;A61K38/00;A61K49/00;A61K49/04;A61K49/06;A61K49/08;A61K49/10;A61K51/00;C07D257/02;C07D295/26;C07D405/12;C07D405/14 |
主分类号 |
C07D257/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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