摘要 |
PROBLEM TO BE SOLVED: To provide a medical device having a surface which comprises a coating layer, capable of preventing coagulation or thrombus formation.SOLUTION: The present invention provides a medical device, such as catheters, stents, stent-grafts, and artificial blood vessels, having a functionalized polyamine surface having a heparin moiety capable of interacting with mammalian blood to prevent coagulation or thrombus formation, through a linker comprising a thioether.SELECTED DRAWING: None |