发明名称 |
SWCNT BIOSENSOR FOR DETECTING GLUCOSE, LACTATE, AND UREA |
摘要 |
A single-walled carbon nanotube-based micron scale multiplex biosensor is provided that enables the detection of glucose, lactate, and urea. The sensor is based on modification of semiconducting single-walled carbon nanotubes using a linker that non-covalently associates with the nanotubes and covalently couples to an enzyme. Reaction of a physiological substrate with the enzyme results in increased resistance of the nanotubes within the sensor. The sensor is suitable for use in patient monitoring, particularly in a clinical setting. Incorporation of read out electronics and an RF signal generator into the sensor device enables it to communicate to a relay station or remote receiver. Methods are also provided for fabricating the biosensor device and using the device for detection. |
申请公布号 |
EP3030891(A1) |
申请公布日期 |
2016.06.15 |
申请号 |
EP20140835240 |
申请日期 |
2014.08.05 |
申请人 |
NORTHEASTERN UNIVERSITY |
发明人 |
LEE, JIN YOUNG;BUSNAINA, AHMED;CHO, HANCHUL;SOMU, SIVASUBRAMANIAN |
分类号 |
G01N27/327;C12Q1/54;C12Q1/58 |
主分类号 |
G01N27/327 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|