| 摘要 |
(I), which is an intermediate for L-dopa and is itself useful as a pharmaceutical, is produced in high yields and purity by (a) preparing from DL-N-benzoyl-3-methoxytyrosine and aniline or a nuclear-substd aniline in a buffered aq. soln of approx. pH 5-7 in the presence of a protease which is active in this pH range (e.g. bromelain, papain, ficin, or a bacterial or fungal protease) an L-N-benzoyl-3-methoxy-tyrosyl-anilide and (b) hydrolysing this to (I) in a conventional manner. |
