摘要 |
An integral, multi-compartment, disposable packaging means, made from flexible sheet material, such packaging means providing for indirect heat exchange between compartments and selective discharge of one compartment independent of a remaining compartment. A first compartment is adapted to receive and store a packaged product; walls for a second compartment are formed integrally with the first compartment establishing a sealed space for effecting indirect heat exchange between the two compartments; a reactive material capable of sustaining an endothermic or an exothermic reaction when mixed with an activating agent is held in one of such compartments. Structural means are provided enabling additives to be made independently to the two compartments and for optimum and more uniform heat transfer. In a specific embodiment, cardioplegic solution held in a first compartment is chilled sufficiently to provide a phase change in at least a portion of the solution by an endothermic reaction in a second compartment which establishes a sealed space surrounding a major portion of the first compartment. The entire packaging unit is sterilized for use in sterile environments such as operating rooms. The cardioplegic solution is discharged in a sterile condition without opening said second compartment or exposing its heat exchange media.
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