Prosthesis having a plurality of distal and proximal prongs

摘要

A prosthesis can be deployed within a body cavity. The prosthesis can include an expandable frame, a plurality of proximal prongs, and a plurality of distal prongs. Each prong of the proximal and distal pluralities is connected to the frame. When the frame is expanded, the ends of the prongs are positioned radially outward from the frame. The frame is configured such that radial expansion of the frame causes the ends of the proximal prongs and the ends of the distal prongs to draw closer together.

主权项

1. A prosthesis configured to be deployed within a native heart valve comprising an opening surrounded by surrounding body tissue of the native heart valve, the surrounding body tissue having a first side and a second side opposite the first side, the prosthesis comprising:
an expandable frame comprising a proximal end and a distal end and a longitudinal axis extending therethrough, the expandable frame comprising a plurality of cells configured to permit the frame to radially expand and collapse for deployment within an opening of the native heart valve, wherein the cells have a generally diamond shape with four vertices when the frame is in an expanded configuration, wherein the frame comprises a laser-cut metal tube; a valve seated inside the expandable frame; a plurality of proximal anchors each connected to the frame so that when the frame is in an expanded configuration within the opening of the native heart valve, an anchoring portion of each proximal anchor extends distally to a distalmost portion of the proximal anchor that is positioned radially outward from the frame; and a plurality of distal anchors each connected to the frame and so that when the frame is in an expanded configuration within the opening of the native heart valve, an anchoring portion of each distal anchor extends proximally to a proximalmost portion of the distal anchor that is positioned radially outward from the frame; wherein when the frame is in an expanded configuration, at least some of the anchoring portions of at least one of the pluralities of proximal anchors and distal anchors connect to one of the vertices of a generally diamond-shaped cell and curve radially outward before extending respectively, distally or proximally, in an axial direction approximately parallel with each other and with the longitudinal axis; wherein, when the frame is in an expanded configuration, distalmost portions of the plurality of proximal anchors and proximalmost portions of the plurality of distal anchors are spaced apart by less than two cell lengths; and wherein the frame, the plurality of proximal anchors, and the plurality of distal anchors are sized and configured such that radial expansion of the frame causes the proximal anchors and the distal anchors to draw closer together and pinch the first side of the surrounding body tissue of the native heart valve and the second side of the surrounding body tissue of the native heart valve towards each other.