| 摘要 |
1,2,4-triazin-5-one compounds of the general formula (I) <IMAGE> (I) where R is <IMAGE> are prepared by reacting a compound of general formula (II) <IMAGE> (II) in which R is defined above with either (a) a tertiary alcohol of general formula (III) HO-R'(III) in which R' is a t-alkyl group having 4 to 18 carbon atoms, especially t-amyl or t-octyl or preferably t-butyl or (b) an alkene of general formula (IV) <IMAGE> (IV) in which R1 and R2 are the same or different and are hydrogen or an alkyl group and R3 and R4 are the same or different and wherein the alkyl groups in each case can be 1 to 15 carbon atoms and wherein preferably R1 and R2 are hydrogen and R3 and R4 each are methyl to form an alpha -ketocarboxylic acid amide of general formula (V) <IMAGE> (V) and this, in a given case after previous saponification to the free acid, condensed with thiocarbohydrazide <IMAGE> to form a 1,2,4-triazin-5-one compound of general formula (VI) <IMAGE> (VI) and then the mercapto group is methylated. |
