发明名称 |
HYDROXYLATION OF SALICYLIC ACID DERIVATIVES |
摘要 |
<p>The invention disclosed relates to the novel compound 5-amino tetrahydroxy benzoic acid and derivatives thereof, e.g. pharmaceutically acceptable acid addition salts, to a process for the preparation thereof which involves reacting 5-amino salicylic acid with hydroxyl radical, and to a method of using 5-amino tetrahydroxy benzoic acid and derivatives thereof as a biomarker for the presenc e of hydroxyl radical in biological systems.</p> |
申请公布号 |
CA2219012(A1) |
申请公布日期 |
1999.04.17 |
申请号 |
CA19972219012 |
申请日期 |
1997.10.17 |
申请人 |
HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF HEALTH & WELFARE, CANADA |
发明人 |
VINCENT, RENAUD;KUMARATHASAN, PREMKUMARI |
分类号 |
C07C229/64;C07F7/18;G01N33/84;(IPC1-7):C07C229/64;A61K49/00;C07F7/10;C07K1/113;C07K2/00;G01N33/48;G01N33/53 |
主分类号 |
C07C229/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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