DENTAL PLAQUE FORMATION INHIBITOR

摘要

PROBLEM TO BE SOLVED: To obtain the subject inhibitor free from irritating odor, capable of suppressing the dental plaque formation without killing normal oral bacteria and capable of preventing the occurrence of dental caries and periodontal diseases by compounding a specific isothiocyanate compound. SOLUTION: An isothiocyanate compound having the formula: CH1 =CH (CH2 )m NCS [(m)=2-10] (e.g. 3-butenyl isothiocyanate or 4-pentenyl isothiocyanate) or an isothiocyanate compound having the formula: RS(CH2 )n NCS [(n)=1-10; R is a 1-4C alkyl] (e.g. methylthiomethyl isothiocyanate or ethylthiomethyl isothiocyanate) is compounded in an oral hygienic agent or a drink in a concentration of about 0.01-100 ppm.