| 发明名称 |
Di-aryl ethers and their derivatives as anti-cancer agents |
| 摘要 |
The present invention relates, inter alia, to compounds that bind tubulin and exhibit anti-mitotic properties and to methods of using such compounds to inhibit abnormal cell mitosis and, in particular, to inhibit tumor cell growth. In addition, methods are presented of treating mammalian diseases associated with undesired and uncontrolled angiogenesis.
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| 申请公布号 |
US6169104(B1) |
申请公布日期 |
2001.01.02 |
| 申请号 |
US19980047945 |
申请日期 |
1998.03.25 |
| 申请人 |
LARGE SCALE BIOLOGY CORPORATION;SRI INTERNATIONAL |
发明人 |
TUSE DANIEL;CHEN XIAOYING;HIEBERT CHARLES K.;OLSEN CRIS M.;LADEROUTE KEITH;WALEH NAHID;KNAPP A. MERRILL |
| 分类号 |
A61P35/00;A61K31/085;A61K31/09;A61K31/095;A61K31/10;A61K31/11;A61K31/12;A61K31/19;A61K31/192;A61K31/235;A61K31/65;A61K41/00;A61P43/00;C07C45/29;C07C47/575;C07C65/24;C07C205/59;(IPC1-7):A61K31/415 |
主分类号 |
A61P35/00 |
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