发明名称 Preparation of 2-alkyl-3-(4,5-dihydroisoxazol-3-yl) halobenzenes
摘要 A novel process for preparing the compounds of the formula Iwhere:n is 0, 1 or 2;R<1>, R<2 >are C1-C6-alkyl;R<3>, R<4>, R<5 >are hydrogen or C1-C6-alkyl, or R<4 >and R<5 >together form a bond;R<6 >is Cl, Br,which comprises a synthesis sequence starting from 1,2-dialkylbenzenes of the formula IIwith subsequent halogenation to give 3,6-dihalo-1,2-dialkylbenzenes, haloalkylation to give benzyl bromides, oxidation to give benzaldehydes, oximation, reaction with alkenes to give isoxazoles, conversion into thioethers and, if appropriate, oxidation to give sulfenyl or sulfonyl derivatives of the formula I.
申请公布号 US6716989(B2) 申请公布日期 2004.04.06
申请号 US20030462903 申请日期 2003.06.18
申请人 BASF AKTIENGESELLSCHAFT 发明人 RACK MICHAEL;GOETZ NORBERT;HAGEN HELMUT;VON DEYN WOLFGANG;BAUMANN ERNST;LOCHTMAN RENE;GEBHARDT JOACHIM
分类号 C07D261/04;(IPC1-7):C07D261/18 主分类号 C07D261/04
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