发明名称 2-{8 (Dihydroisoquinolinyl or dihydroisoindol-2-yl)alkyl{9 -1H-benz{8 de{9 isoquinoline-1,3(2H)-diones
摘要 Compounds of the following formula and their acid addition salts WHEREIN R1, R2, R3, and R4 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, amino and trifluoromethyl; A is a straight or branched chain alkylene of 1 to 8 carbons; and m is 1 or 2 are disclosed. These compounds exhibit antidepressant and anti-anxiety activity. In addition these compounds are useful as antiinflammatory agents.
申请公布号 US3947452(A) 申请公布日期 1976.03.30
申请号 US19750538976 申请日期 1975.01.06
申请人 E. R. SQUIBB & SONS, INC. 发明人 WADE, PETER C.;VOGT, BERTHOLD RICHARD
分类号 C07D221/14;(IPC1-7):C07D401/06;C07D217/24 主分类号 C07D221/14
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