Ruthenium catalyst for biarylic coupling; new steganolides

摘要

PCT No. PCT/FR87/00055 Sec. 371 Date Nov. 5, 1987 Sec. 102(e) Date Nov. 5, 1987 PCT Filed Mar. 5, 1987 PCT Pub. No. WO87/05289 PCT Pub. Date Sep. 11, 1987.A method for forming bridged biaryl compounds via the intramolecular oxidative biarylic coupling of precursor compounds containing two aromatic rings linked via a hydrocarbon chain is disclosed along with the ruthenium catalyst for its implementation and new compounds resulting therefrom. The biarylic coupling method is characterized in that the biarylic precursors are cyclized in the presence of the catalyst tetrakis(trifluoroacetate) of ruthenium (IV).