1-METHYLCARBAPENEM DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIBIOTICS

摘要

Compounds of formula (I): (I) wherein: R1 is hydrogen or an unsubstituted or substituted alkyl group; and A represents a number of cyclic or acyclic nitrogen-containing groups are valuable antibiotics which are resistant to dehydropeptidase I in vivo. Methods of preparing the compounds and of using them are also disclosed.