发明名称 |
PROTEOMIC ANALYSIS WITH NUCLEIC ACID IDENTIFIERS |
摘要 |
Disclosed are methods and compositions for labeling target molecules or associated target molecule tags with origin-specific nucleic acid barcodes. The identity, quantity, and/or activity of target molecules originating from particular discrete volumes, such as droplets, for example water-in-oil emulsions, can be determined by determining the sequence of the origin-specific nucleic acid barcodes (optionally in combination with additional barcodes, such as one or more additional nucleic acid and/or peptide barcode). |
申请公布号 |
WO2016145416(A3) |
申请公布日期 |
2016.10.13 |
申请号 |
WO2016US22211 |
申请日期 |
2016.03.11 |
申请人 |
THE BROAD INSTITUTE, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
GORDON, David, Benjamin;NICOL, Robert;VOIGT, Christopher;PARK, Yongjin;ROCKWELL, Graham, N.;DWIVEDI, Ritika |
分类号 |
A61K38/00;C12N15/09;C12N15/10;C12Q1/68;G01N33/53 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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