发明名称 |
METHOD OF OBTAINING ANTIGENICALLY STRENGTHENED ENTEROBACTERIA AND VACCINES CONTAINING THEM |
摘要 |
Methods using in vitro processes are disclosed for inducing or enhancing expression of enteric bacterial antigens or virulence factors. The methods, therefore, produce antigenically enhanced enteric bacteria. Also methods for using the antigenically enhanced bacteria are also disclosed, as well as vaccines containing the enteric bacteria. Specifically a whole enteric bacterium or components thereof are provided by Helicobacter species. Also there are other enteric bacteria which are useful for the disclosed invention; such as Campylobacter jejuni. |
申请公布号 |
PL319583(A1) |
申请公布日期 |
1997.08.18 |
申请号 |
PL19950319583 |
申请日期 |
1995.10.04 |
申请人 |
MICROCARB INC |
发明人 |
PACE JOHN L.;WALKER RICHARD I.;FREY STEVEN M. |
分类号 |
A61K39/02;A61P31/04;A61P37/04;C12N1/20;C12Q1/04;C12Q1/18;C12R1/01;G01N33/15;G01N33/569 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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