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发明名称
唑并嘧啶衍生物之制法
摘要
申请公布号
TW049615
申请公布日期
1983.04.01
申请号
TW07110677
申请日期
1982.02.23
申请人
持田制药株式会社
发明人
大西治夫;小雀浩司;持田英;铃木泰雄
分类号
A61K31/415;A61K31/505;C07D513/04
主分类号
A61K31/415
代理机构
代理人
林敏生 台北巿南京东路二段一二五号七楼伟成第一大楼
主权项
1.将式(I) HN(C2H5)2 (I) 所表示之二烷基胺和4,6-二 氯-2-甲基-5-硝基嘧啶反应, 得到(II) 所表示之化合物,再将它和氢硫 化钠反应,使嘧啶环之氯原子置换成 氢硫基后,将环中硝基还原;得到式 (III)所表示之化合物 再把它和式(IV) H.COOH (IV) 所表示之有机酸缩合,以获得式 (v) 所表示之 唑并嘧啶衍生物之制法。
地址
日本国东京都新宿区西谷1丁目7番地
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