DIAGNOSTISKT FORFARANDE IN VITRO SAMT MEDEL SOM KAN UTNYTTJAS VID FORFARANDET

摘要

Method for the in vitro diagnostication of diseases associated with fibrin(ogen)olysis and/or pathological elastase activity, characterized in that a sample taken from a patient and containing fibrinopeptides is subjected to quantification of at least one elastase induced B beta 14(+/-2) - 45(+/-3) fibrinopeptide(s). The value thus obtained is compared with a normal value for healthy individuals, and that if the value obtained is higher than said normal value the patient from whom the sample has been taken is classed as being diseased. The assay method provides a way of demonstrating the presence of free elastase activity in samples taken from patients. Furthermore, novel antibody preparations as well as novel elastase induced B beta 14(+/-2) - 45(+/-3) fibrinopeptide preparations are described which may be employed in the said method.