Devices, methods and kits for delivery of therapeutic materials to a target artery

摘要

An apparatus includes an inner catheter that is coupled to a handle and defines a lumen configured to receive a guidewire. An outer catheter is movably coupled to the handle and defines a first lumen in fluid communication with a distal opening and that is configured to introduce a therapeutic agent through the distal opening and into a target pancreatic artery(ies). The outer catheter defines a second lumen configured to receive at least a portion of the inner catheter. An actuator is coupled to the handle and configured to move the outer catheter relative to the handle. A first occlusion element is coupled to the inner catheter and a second occlusion element is coupled to the outer catheter and disposed proximal to the first occlusion element. A distance between the first occlusion element and the second occlusion element is adjustable when the outer catheter is moved relative to the handle.

主权项

1. An apparatus, comprising:
an inner catheter defining an inner catheter lumen configured to receive a guidewire; an outer catheter defining a first lumen in fluid communication with an opening defined in a side wall at a distal end portion of the outer catheter and configured to introduce a therapeutic agent through the opening and into one or more target arteries, and a second lumen configured to receive at least a portion of the inner catheter; a first port coupled to the outer catheter in fluid communication with the first lumen; a second port coupled to the outer catheter in fluid communication with the second lumen; a first occlusion element coupled to the inner catheter; and a second occlusion element coupled to the outer catheter, the second occlusion element disposed proximal to the first occlusion element, a distance between the first occlusion element and the second occlusion element being adjustable when at least one of the outer catheter and the inner catheter is moved relative to other of the outer catheter and the inner catheter.