发明名称 Compositions of alkylbenzenes in film-forming materials for visualization of the gastrointestinal tract
摘要 Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula <IMAGE> and methods for their use in diagnostic radiology of the gastrointestinal tract wherein R=C1-C25 alkyl, cycloalkyl, unsaturated allyl or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR1R2)p-(CR3=CR4)mQ, or (CR1R2)p-C 3BOND C-Q; R1, R2, R3 and R4 are independently H, lower-alkyl, optionally substituted with halo; n is 1-5; m is 1-5; p is 1-10; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl.
申请公布号 US5334370(A) 申请公布日期 1994.08.02
申请号 US19930013459 申请日期 1993.02.04
申请人 STERLING WINTHROP INC. 发明人 JOSEF, KURT A.;BACON, EDWARD R.;ESTEP, KIMBERLY G.;ILLIG, CARL R.;DOUTY, BRENT D.
分类号 A61K49/04;C07C17/12;C07C17/26;C07C17/354;C07C25/02;C07C69/65;(IPC1-7):A61K49/04;C07C69/76;C07C22/00;C07C25/00 主分类号 A61K49/04
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