| 发明名称 |
COMBINATION OF AN ARSENIC COMPOUND AND AT LEAST ONE RETINOID FOR TREATING ACUTE MYELOID LEUKEMIA |
| 摘要 |
The present invention relates to methods and pharmaceutical compositions for the treatment of acute myeloid leukemia. In particular, the present invention relates to a method for treating NPM-1-driven acute myeloid leukemia (AML) in a subject in need thereof comprising administering the subject with a therapeutically effective amount of at least one arsenic compound and with a therapeutically effective amount of at least one retinoid. |
| 申请公布号 |
US2016317579(A1) |
申请公布日期 |
2016.11.03 |
| 申请号 |
US201415107749 |
申请日期 |
2014.12.30 |
| 申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE ;UNIVERSITE PARIS DIDEROT- PARIS 7 ;UNIVERSITA DI PERUGIA ;AMERICAN UNIVERSITY OF BEIRUT ;ASSISTANCE PUBLIQUE -HÔPITAUX DE PARIS (APHP) |
发明人 |
De The Hugues;Bazarbachi Ali;El Hajj Hiba;Martelli Maria Paula;Falini Brunangelo |
| 分类号 |
A61K33/36;A61K31/203 |
主分类号 |
A61K33/36 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating NPM-1-driven acute myeloid leukemia (AML) in a subject in need thereof comprising administering to the subject a therapeutically effective amount of at least one arsenic compound and a therapeutically effective amount of at least one retinoid. |
| 地址 |
Paris FR |
