T-cell death-inducing epitopes

摘要

Cell death-inducing epitopes and polypeptides containing same. Also disclosed are compounds for inducing death of activated T-cells, a method of producing antibodies to the epitopes, a method of identifying compounds that bind to the epitopes, a method of inducing death of activated T-cells, and pharmaceutical compositions containing the compounds.

主权项

1. An isolated polypeptide comprising SEQ ID NO: 20 or SEQ ID NO: 22, wherein binding of a ligand to the polypeptide on activated T-cells induces death of the cells.