摘要 |
A filter means (36) which forms a frequency-selective attenuator (FSA) to attenuate the series resistance compensation signal (Vcomp) of a voltage clamp (5) having an undesired series resistance (Rs). Filter means (36) increases the stability and eliminates the steady-state error of series resistance compensation without compromising the compensated bandwidth, and without requiring excessive bandwidth of the compensation signal (Vcomp) to ensure stability. Filter means (36) also enables the compensated bandwidth and the rate of steady-state error elimination to be selected. Filter means (36) is particularly suited to improving the series resistance compensation of voltage clamps that measure ionic current in biological preparations, allowing rapid ionic current in excitable cells to be voltage clamped.
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