| 发明名称 |
DEPLETION OF PLASMACYTOID DENDRITIC CELLS |
| 摘要 |
The present invention relates to antibodies targeted to BDCA2 that deplete plasmacytoid dendritic cells (pDC) and methods of using the antibodies to treat disorders associated with pDC. |
| 申请公布号 |
US2016280790(A1) |
申请公布日期 |
2016.09.29 |
| 申请号 |
US201615092275 |
申请日期 |
2016.04.06 |
| 申请人 |
The University of North Carolina at Chapel Hill |
发明人 |
Su Lishan |
| 分类号 |
C07K16/28;C12N5/00 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of depleting plasmacytoid dendritic cells (pDC) in a subject, comprising delivering to the subject an effective amount of an antibody or a fragment thereof that specifically binds to blood dendritic cell antigen-2 (BDCA2) and depletes pDC, thereby depleting pDC. |
| 地址 |
Chapel Hill NC US |
