PHARMACEUTICAL COMPOSITIONS FOR INTRANASAL ADMINISTRATION OF [2-(8, 9-DIOXO-2, 6-DIAZABICYCLO [5.2.O] NON-1 (7)-EN- 2-YL) ALKYL] PHOSPHONIC ACID AND DERIVATIVES AND METHODS OF USE THEREOF.

摘要

Pharmaceutical compositions for intranasal administration are provided that contain at least one compound of formula (I) or a pharmaceutically acceptable salt thereof: and one or more pharmaceutically acceptable additives for forming a composition for intranasal administration. Also provided are methods of treating one or more conditions in a mammal associated with a glutamate abnormality that includes administering intranasally to a mammal a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof.