| 摘要 |
The process comprises the following steps: a. Protection of the amino group of aspartic acid resulting in an N-protected derivative in the form of free diacid or an amine salt. b. Preparation of a mixed anhydride of N-protected aspartic acid and one carboxylic acid, followed immediately by condensation with an amino acid or an amino acid derivative, which results in an N-protected aspartyl peptide. c. Deprotection resulting in the aspartyl peptide. Using, as amino acid derivative, methyl L-phenylalaninate, methyl alpha -aspartyl-L-phenylalaninate is obtained.
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