发明名称 Process for the preparation of a viral agent responsible for post-transfusion non-A non-B hepatitis
摘要 The invention relates to a process for the preparation of a viral polypeptide responsible for post-transfusion non- A non-B hepatitis (PT-NANBH), which involves cloning or synthesizing a DNA sequence that codes for an antigen having an amino acid sequence which is at least 90% homologous with the amino acid sequence given in the sequence identified by SEQ ID NO: 3, 4, 5, 18, 19, 20, 21 or 22, or an antigenic fragment thereof, inserting the DNA sequence into an expression vector such that it can be expressed in a suitable host, transforming a host cell with the expression vector, culturing the transformed host cell, and isolating the viral polypeptide.
申请公布号 PT96223(A) 申请公布日期 1991.09.30
申请号 PT19900096223 申请日期 1990.12.17
申请人 THE WELLCOME FOUNDATION LTD. 发明人 PETER EDMUND HIGHFIELD;BRIAN COLIN RODGERS;RICHARD SETON TEDDER;JOHN ANTHONY JAMES BARBARA
分类号 C12N15/00;C12N15/86;C12P21/00;(IPC1-7):C12P21/00 主分类号 C12N15/00
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