PHYSIOLOGICALLY ACTIVE SUBSTANCE BE-16627.

摘要

A physiologically active substance BE-16627 which is a novel inhibitor of stromelysin (human), represented by general formula (I), wherein R is a hydrogen atom or a methyl group, or a pharmaceutically acceptable salt thereof. Also disclosed are a process for preparing the same, a use of the same as a therapeutic agent for rheumatism and a cancer metastasis inhibitor, and a microorganism which produces BE-16627.