| 摘要 |
This invention relates to certain 2,6-dialkyl-4-silyl- phenols of the formula: wherein R1, R2, R3 and R4 are each independently a C1-C6 alkyl group; Z is a thio, oxy or methylene group; A is a C1-C4 alkylene group; and R5 is a C1-C6 alkyl or -(CH2)n-(Ar) wherein n is an integer 0, 1, 2 or 3, and Ar is phenyl or napthyl unsubstituted or substituted with one to three substituents selected from the group consisting of hydroxy, methoxy, ethoxy, chloro, fluoro or C1-C6 alkyl; which are useful as inhibitors of LDL lipid peroxidation and as antiatherosclerotic agents.
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