VIRUS-MODIFIED TUMOUR VACCINE FOR THE IMMUNOTHERAPY OF TUMOUR METASTASES

摘要

PCT No. PCT/EP89/00186 Sec. 371 Date Dec. 28, 1989 Sec. 102(e) Date Dec. 28, 1989 PCT Filed Feb. 27, 1989 PCT Pub. No. WO89/07946 PCT Pub. Date Sep. 8, 1989.The invention discloses a virus-modified tumour-specific vaccine consisting of corresponding separated tumour cells inactivated by irradiation and incubated with NDV (Newcastle Disease Virus) under sterile conditions in serum-free medium. The vaccine may optionally be irradiated again prior to application.