| 发明名称 |
Crystals of an antimicrobial compound. |
| 摘要 |
<p>A method for selectively obtaining any one of an anhydrate, a 1/2 hydrate, a 1 hydrate, and a 3/2 hydrate of 7-[(7-(S)-amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2 S)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3- carboxylic acid is disclosed, comprising treating the compound in an aqueous solvent or water or recrystallizing the compound from an aqueous solvent or water. <IMAGE> <IMAGE> <IMAGE> <IMAGE></p> |
| 申请公布号 |
GR3031012(T3) |
申请公布日期 |
1999.12.31 |
| 申请号 |
GR19990402090T |
申请日期 |
1999.08.18 |
| 申请人 |
DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
KIMURA, YOUICHI;KAWAKAMI, KATSUHIRO;MIKATA, NORIMASA;UCHIYAMA, KEIJI;UEMURA, TAZUO;YUKIMOTO, YUSUKE |
| 分类号 |
C07D401/04;A61K31/47;A61K31/4747;A61P31/04;A61P35/04;C07B63/00;C07D215/56;C07D221/00;C07D401/10;C07D403/04;C07D471/04;(IPC1-7):C07D401/04 |
主分类号 |
C07D401/04 |
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