| 摘要 |
PROBLEM TO BE SOLVED: To obtain a composition for the mouth having a high surface coverage on oral mucosa and having high protective and treating activities on periodontal diseases by adding a specific active agent or antimicrobial agent, and a heat generating body or a water-soluble polymer, and specifying a water content. SOLUTION: This composition is obtained by adding (A) 0.1-5 wt.% of (i) an active agent or (ii) an antimicrobial agent, which acts on periodontal tissue, (B) (iii) 5-50 wt.% of a heat generating body or (iv) 0.1-2 wt.% of a water-soluble polymer, and (C) optionally an alkaline earth metal salt, and controlling the water content at 5 wt.% or less, preferably 3 wt.% or less. Examples of the component i include a circulation accelerator, an antiinflammatory agent, a hemostatic agent, an analgesic, an antihistaminic and a plant extract having a drug action thereof. Examples of the component iii include heat generating substances which generate heat by hydration reaction in the mouth, and it is used preferably under such conditions that the temperature of the component becomes 38-50 deg.C, preferably 40-45 deg.C by hydration.
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