COMPOSITION CONTAINING 2-HYDROXYMETHYL-3-PHENYL-4-(3H)-QUINAZOLINONE

摘要

1443829 Production of 2-hydroxy-3-phenyl- 4(3H)-quinazolinone M INOUE M ISHIKAWA T TSUCHIYA and T SHIMAMOTO 11 June 1973 [12 June 1972] 27718/73 Heading C2C [Also in Division A5] A novel process for producing 2-hydroxymethyl-3-phenyl-4(3H)-quinazoline and its acid addition salts comprises reacting a compound of the Formula II wherein R 1 is halogen, acetoxy, benzoyloxy or benzyloxy with aniline in the presence of a condensing agent to produce a compound of the Formula III and either hydrolysing or, if R 1 is benzyloxy hydrogenating the compound III to produce the required compound.