11*11AMINOALKYL*TRICYCLO 4*3*1*12*5 UNDECANE

摘要

NEW MATERIAL:The title compound of formula I (R is lower alkyl). EXAMPLE:1-(1-Aminoethyl)tricyclo[4.3.1.1<2>,<5>]undecane. USE:Remedy for Parkinson's disease. Active to RNA virus and extremely effective against herpes virus (DNA virus). Esp. useful for viral diseases of man and animals. PROCESS:A compound of formula I is obtained by the reduction of oxime of formula II. The compound of formula II can be obtained as follows: A known halide of formula III (X is halogen) is made to react with a formate in the presence of sulfuric acid to give a compound of formula IV, which is converted to an acid halide of formula V. Then the acid halide obtained is made to react with dialkyl cadmium to give a ketone of formula VI which is made to react with hydroxylamine.