PROCESS FOR THE PREPARATION OF AROMATIC-1,4-OXAZEPINONES AND THIONES

摘要

1,4-Oxazepinones and thiones of general formula I; …… wherein A is an aromatic ring selected from benzene, naphthalene, quinoline or pyridine; n is 1 to 3; Z is an amino radical; R hydrogen, loweralkyl, cycloalkyl or phenyl-loweralkyl; and R<4> and R<5> are hydrogen and loweralkyl, may be prepared by cyclizing a compound of general formula II or general formula III: …… which in turn may be prepared from chloroaromatic carboxylates and alkanolamines.