发明名称 |
Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides |
摘要 |
A process for the preparation of 2-alkyl-6-methyl-N(1'-methoxy-2'-propyl)-aniline by catalytic reductive alkylation wherein at least one mole equivalent of methoxyacetone is reacted with one mole equivalent of 2-alkyl-6-methyl-aniline in a liquid medium without an additional solvent, in the presence of a platinized carbon catalyst and hydrogen and in the presence of an acid cocatalyst under a hydrogen pressure of between 2x105 and 1x106 Pa at a temperature between 20 DEG and 80 DEG C., characterized in that the reaction mixture contains water from the beginning of the reaction and after the hydrogenation, base is added, the reaction mixture is filtered to separate the catalyst and the title compound recovered from the filtrate. The process is particularly useful for the preparation of N-substituted chloracetanilide herbicides.
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申请公布号 |
US5430188(A) |
申请公布日期 |
1995.07.04 |
申请号 |
US19930168034 |
申请日期 |
1993.12.15 |
申请人 |
CIBA-GEIGY CORPORATION |
发明人 |
BADER, ROLF;FLATT, PETER;RADIMERSKI, PAUL |
分类号 |
B01J27/02;C07B61/00;C07C209/26;C07C213/02;C07C213/08;C07C217/08;C07C231/00;C07C231/02;C07C233/18;(IPC1-7):C07C231/08 |
主分类号 |
B01J27/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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