| 摘要 |
The invention discloses the amino acid sequence of Acyl-Peptide Hydrolase. The invention relates to a DNA molecule encoded for Acyl-Peptide Hydrolase, a vector incorporating the molecule, and the use of such vector to transform a host. The invention further relates to the expression by the host to produce Acyl-Peptide Hydrolase, and the use of APH to catalyze the hydrolysis of an N alpha -acetylated peptide or protein or the reaction between an N alpha -acetyl amino acid donor and an acceptor protein with a free alpha -NH2 group. The invention further relates to the use of the Acyl-Peptide Hydrolase-encoding sequences in the detection of cancer.
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