发明名称 PLANTES TRANSGENIQUES EXPRIMANT LA GLYCOPROTEINE G DE LA RAGE, ET GLYCOPROTEINES AINSI OBTENUES
摘要 This invention features a method for producing the glycoprotein G of the rabies virus, or a virus related to the rabies virus, characterised by: i) introducing, into a plant cell, a nucleic acid molecule comprising a chimeric coding sequence, comprising one coding sequence for the said mature viral protein G, or for an analogous protein, and a coding sequence for a N-terminal signal peptide other than the one naturally associated with the viral protein G, enabling the expression of the protein G in the cell; ii) multiplying, in the form of cell culture, transformed cells, or regeneration of whole transgenic or chimerical plants from these cells; iii) optionally extracting and purifying the glycoprotein G from the cells or plants thus obtained.
申请公布号 FR2748480(A1) 申请公布日期 1997.11.14
申请号 FR19960006029 申请日期 1996.05.09
申请人 BIOCEM 发明人 MEROT BERTRAND;BAUDINO SYLVIE;GRUBER VERONIQUE;BOURNAT PHILIPPE;LENEE PHILIPPE;RIVIERE MICHEL EMILE ALBERT;AUDONNET JEAN CHRISTOPHE FRANCIS
分类号 A61K39/00;C07K14/145;C12N15/40;C12N15/82;(IPC1-7):C07K14/415;C07K16/10;C12N15/47;C12N15/84;C12N5/10;A01H5/00;A01H5/10;A61K39/205;A61K48/00;A61K35/78 主分类号 A61K39/00
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