发明名称 4,5,6,7-tetrahydroindazole derivatives as antitumor agents.
摘要 Compounds which are 4,5,6,7-tetrahydroindazole derivative formula (1), wherein the dotted line (x) represents a single or double bond; n is 0 or 1; R1, R2 and R3 have the meanings reported in the description; Ra, R'a, Rb, R'b, Rc, R'c have the meanings reported in the description, also comprising that Ra and Rb together and/or Ra and Rc together form a N-alkylpiperydinyl ring with 1 to 6 carbon atoms in the alkyl chain or a phenyl ring; or pharmaceutically acceptable salts thereof, are useful for treating cell proliferative disorders and Alzheimer's disease.
申请公布号 ZA200108530(B) 申请公布日期 2003.02.03
申请号 ZA20010008530 申请日期 2001.10.17
申请人 PHARMACIA & UPJOHN S.P.A. 发明人 PAOLO PEVARELLO;MANUELA VILLA;MARIO VARASI;ANTONELLA ISACCHI
分类号 A61K31/416;A61K31/4439;A61P9/10;A61P17/06;A61P17/14;A61P25/28;A61P35/00;A61P43/00;C07D231/56;C07D401/04 主分类号 A61K31/416
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